This is the historic Brown Hotel in Louisville, Kentucky. This 16 story structure was built in 1923 and originally had 600 room. Now, after some reorganizing, there are 293 more spacious rooms and additional meeting and banquet space. The Brown was added to the National Registry of Historic Places in 1978.
Elizabethtown came out in 2005 and starred Orlando Bloom and Kirsten Dunst. Susan Sarandon and Alec Baldwin also played prominent roles.